IL6 and hereditary elliptocytosis: We observed that IL-6 levels were higher in HE-control relative to LE-control (P = 0.0119) and in HE-PSD+US in relation to LE-PSD+US {P = 0.0207; two-way ANOVA significant main effect of “exploratory activity” [F (1, 30) = 20.57, P < 0.0001]}.