NFKB1 and intervertebral disk degenerative disorder: Luteoloside suppresses the inflammation response by inhibiting the degradation of nuclear factor-kB inhibitor (IkB), an indicator of the activation of nuclear factor-kB (NF-kB) (Hsuan et al., 2015), which is closely associated with IDD (Yao et al., 2016; Li et al., 2017).