Reduces tumor sizeReduces colon shorteningReduces distal colon tumorogenesisReduces COX-2 protein expressionRepresses NF-κB transcriptional activationReduces mucosal PGE2 levelsPreserves tumor suppressive 15-PGDH gene expressionReduces proliferationReduces β-catenin nuclear translocationIncreases apoptosisIncreases apoptotic molecules FAS and BaxReduces expressions of antiapoptotic molecules survivin and Bcl-2. This evidence concerns the gene BIRC5 and neoplasm.