Differences in thalamic, insula and amygdalar-hippocampal GMV have not been reported in the meta-analysis, but were found in univariate analysis of obesity-related factors such as CRP (Corlier et al., 2018), HbA1c (Reitz et al., 2016), and BMI (Kharabian Masouleh et al., 2016). The gene discussed is CRP; the disease is obesity disorder.