The univariate analysis showed that the IL-18, IFN-γ, IL-6, Glu, CREA, and D-dimer levels; gender; and smoking status exhibited a trend towards an association with the presence of AD, whereas SBP, DBP, the TG level, the TC level, the CRP level, the WBC count, age, and HR showed no obvious association. The gene discussed is IL18; the disease is Alzheimer disease.