The associated genes included for example several genes with known immune related functions such as BCL10, HLA-G, IGJ, SOX4, IFIT2, IRGM, F2RL1, STAMBP, GIMAP4, small RNA regulation like TNRC6B, TDRKH, and neuronal function related GMFB, NEFL. Several of these genes have been reported earlier in the context of MS, thus confirming the biological relevance of the genes discovered here by using an integration of cell-specific transcriptional profiles. This evidence concerns the gene F2RL1 and myeloid sarcoma.