Of note, one of them carried the same STAP1 variant (rs199787258, c.526 C > T, p.Pro176Ser) that we had observed in the Berlin FH cohort, suddenly associated with almost normal lipid parameters at the age of 54 years: TC 206 mg/dl (reference TC <200 mg/dl), LDL-C 111 mg/dl (reference LDL-C <115 mg/dl), HDL-C 82 mg/dl (reference HDL-C in females >45 mg/dl), and TG 81 mg/dl (reference TG 30–150 mg/dl). Here, STAP1 is linked to familial hyperaldosteronism.