LDLR and familial hyperaldosteronism: On a molecular level, diagnosis of FH can be confirmed by presence of a heterozygous pathogenic mutation in one of three genes: LDLR (low density lipoprotein receptor, OMIM 606945)5,6, APOB (apolipoprotein B, OMIM 107730)7,8 and PCSK9 (proprotein convertase subtilisin/ kexin, OMIM 607786)9.