Western blot analysis showed that similar to the results of the HOMA-IR index, at 1 week after treatment, compared with T2D, both UC-MSCs alone and UC-MSCs plus decitabine significantly increased p-AKT expression (P < 0.05), and there was no significant difference between the two groups (Fig. 2d). The gene discussed is AKT1; the disease is type 2 diabetes mellitus.