CDH4 and central nervous system cancer: An updated analysis on the public repository Rembrandt (Betastasis, available online: http://www.betastasis.com/glioma/rembrandt) confirmed the prognostic value of Cdh4 expression level on both all glioma subtypes (n= 329; p < 0.001) and glioblastoma alone (n = 178; p < 0.02; Figure 1a,b).