As shown in Figure 3i–n and quantified in Figure 3o–q, β-catenin has mainly a cytoplasmic localization in both Cdh4 silenced and control GICs, suggesting that the β-catenin pathway is not involved in these gliomas [34,35] as we showed also for the murine model [20]. The gene discussed is CDH4; the disease is central nervous system cancer.