APEX1 and metabolic syndrome: Pairwise comparisons showed an increased ApEn in MetS animals at both weeks 14 (0.74 (0.54) vs. 1.23 (0.18); p = 0.007; r = 0.559) and 28 (0.71 (0.54) vs. 1.15 (0.2); p = 0.015; r = 0.514) (Figure 2A).