Although the extent of the benefit of n-3 PUFA was not high, the high prescription rate of other anti-HF agents in the participants, i.e., angiotensin converting enzyme inhibitor (ACE-I)/angiotensin receptor blocker (ARB) (93%) and β-blocker (BB) (64%), these results allow us to realize the significance of the n-3 PUFA intake in HF patients. This evidence concerns the gene ACE and hydrops fetalis.