Fibroblasts on IPF scaffolds produced significantly higher amounts of tenascin (p = 0.044 at day 3, p = 0.027 at day 9) and periostin (p = 0.039 at day 1) (Figure 6A), protein expression patterns that have been implicated in fibrosis [25,27,28]. This evidence concerns the gene TNC and idiopathic pulmonary fibrosis.