CUGBP1 is thought to regulate translation of certain mRNAs through interaction with the eukaryotic initiation translation factor 2α (eIF2α) mediated by cyclin D3/CDK4 phosphorylation at S302, and it is this activity which may be disrupted in DM1 [83,84]. Here, CCND3 is linked to myotonic dystrophy type 1.