However, we found great variability in LOXL2 serological values, both at baseline and at 24 M, so, given that the levels of LOXL2 may be increased in other chronic pathologies, we subselected the group of patients without relevant comorbidity (chronic renal insufficiency, kidney transplant, psoriasis, or rheumatological diseases). This evidence concerns the gene LOXL2 and chronic kidney disease.