We found that insulin (r = 0.356, p < 0.0001), HOMA (r = 0.385, p < 0.0001), and MetS OR 3.4 (0.700; 6.294; p < 0.001) were the most important factors of advanced fibrosis by Fibroscan® in univariate logistic regression analysis. Here, INS is linked to metabolic syndrome.