Inflammatory cytokines like interleukin (IL)-8 and tumour necrosis factor alpha (TNF-α) are highly expressed and released in airway tissue by various cells (e.g., bronchial epithelial cells, neutrophil leukocytes, tissue macrophages) orchestrating the inflammatory processes in COPD [14]. Here, CXCL8 is linked to chronic obstructive pulmonary disease.