H19 and posterior cortical atrophy: To evaluate whether the H19 downregulation observed in PCa cells was also detectable in tissue samples from patients with prostate cancer (n = 10), a molecular analysis was performed using organotypic slice cultures (OSCs) obtained from fresh surgical explants of organ-confined prostate tumors, as in the work of [40] (Figure S8 and Table 1 for histopathological characteristics of PCa patients).