CRISPLD2 and Sepsis: An independent GWAS study [59] found 14 loci with suggestive evidence of association with 28-day mortality from sepsis in the genes encoding the vacuolar protein sorting 13 homologs A (VPS13A) and the cysteine rich secretory protein LCCL domain containing 2 (CRISPLD2), as well as an intergenic variant at 13q21.33 in an independent data set.