For example, mutations in the chromo, ATPase and Helicase domains in chromodomain 4 (CHD4)—a component of the NuRD/Mi2 complex, in ARID1A encoding BAF250a—a component of SWI/SNF remodeling complexes, and missense mutations in histone H3-lysine-4 methyltransferase MLL3 are frequently found in endometrial cancer [220]. This evidence concerns the gene ARID1A and endometrial cancer.