METTL3 and glioblastoma: Examples of such findings include: association of increased expression of methyltransferases METTL3 and METTL14 with the self-renewal of glioblastoma stem cells via influencing the expression of putative target mRNAs of m6A, such as ADAM19 (Figure 8c) [294]; METTL3 interaction with ribosomes and assistance in translation of target mRNAs [295]; and expression and functionally relevant mutations in METTL3 could influence mRNA translation in the cytoplasm (Figure 8c).