KLF2 and arthritic joint disease: Histological assessment revealed that a higher degree of inflammatory cell infiltration, along with damage to cartilage and bone tissue, were more prominent in the KLF2+/− mice than in KLF2+/+ mice (Figure 1), which is consistent with our previous findings using an methylated bovine serum albumin (mBSA)- and IL-1β-mediated arthritis induction model [19].