In these cells, mouse IFN-αA and IFN-λ3 treatments significantly up-regulated the expression of the IFN-stimulated genes (ISGs) Oasl2 (Figure 1A) and Usp18 (Figure 1B), and significantly decreased infection by TM967, a TMEV derivative expressing mCherry (Figure 1C). Here, IFNL3 is linked to infection.