Expression of serine/glycine metabolism-related proteins, including phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase (PSAT), phosphoserine phosphatase (PSPH), serine hydromethyltransferase (SHMT), and glycine decarboxylase (GLDC), is different in different thyroid cancer subtype as mentioned below. This evidence concerns the gene PSAT1 and thyroid cancer.