Notably, the abnormal NRP1 DNA fragments were found in a subset of primary colorectal tumors (NF99, NF103, NF105, NF106, NF110) and the primary CRC and liver metastasis tumor cell lines (Pt93, Pt2377 and LM2377) at an expression level equal to or above that found for NRP1-WT mRNA (Fig. 1e, f; Supplementary Table 1). The gene discussed is ILF3; the disease is colorectal neoplasm.