Similar results were observed in primary CRC cell lines (Pt93, Pt2377, LM2377) that express endogenous NRP1-∆E4 and/or -∆E5 (Supplementary Figs. 2e, 6c, d, 7a) and in HT29 cells expressing the N-glycosylation-defective NRP1 mutant N150Q or N261Q (Supplementary Figs. 6e, 7b). Here, NRP1 is linked to colorectal carcinoma.