NTRK1 and neoplasm: However, there were several limitations for our cross-species integration: (i) highly limited patient sample availability (i.e. only eight patients with PDGFRA mutations and three patients with NTRK1 fusions) restricted the statistical power; (ii) large variations in the patients (e.g. tumor cells of origin, tumor growth environment, patient age and tumor grade) also confounded the data integration.