Yang et al. reported remarkably decreased expression of miR-181d in ME subtype GBM compared with PN tumors, in both TCGA and CGGA (Chinese Glioma Genome Atlas) cohorts, and attenuated ME phenotype GBM by repressing nuclear factor kappa B (NFκB) transcriptional activity via direct targeting of MALT1 (MALT1 paracaspase) [28]. This evidence concerns the gene NFKB1 and glioma.