HIF1A and renal cell carcinoma: In this meta-analysis, we found that the AA genotype of HIF1α 1790G/A was positively associated with RCC risk in overall populations (OR = 3.09, 95% CI: 1.38–6.92, P = 0.006; Fig. 1 and Table 2) and Caucasians, but not for Asians.