Three cytokines (IL9, PDGF-AA, and PDGF-BB) were identified to be significantly elevated in CM2 compared with the NAF- or BCC-only CMs (Figure 4F) of which, only recombinant PDGF-BB induced IL1β transcript (6.5 ± 0.79 fold) and protein (2.68 ± 0.11 fold) expression in NAFs after 6 and 48 h, respectively (Figures 4G and 4H, Table S2). The gene discussed is IL1B; the disease is skin basal cell carcinoma.