NR3C2 and Hyperkalemia: Clinicaltrials using spironolactone in PD patients, using different definitions ofhyperkalemia, were included in a recent systematic review/meta-analysis to evaluatethe safety and efficacy of the use of MR antagonists in dialysis, which showed thatthe use of MR antagonists was significantly associated with hyperkalemia.41 The present study observed no significantdifferences in serum potassium over time between treatment group and controlpatients.