ATG5 and Menkes disease: And, miR‐130a regulates host antiviral response and HCV replication through targeting ATG5 via the ATG5‐dependent autophagy pathway.146 Bovine viral diarrhea virus (BVDV), the causative agent of bovine viral diarrhea/mucosal disease (BVD/MD), is an important pathogen associated with reproductive, gastrointestinal, and respiratory diseases.