TLR8 and tuberculosis: For instance, several reports revealed that some populations of tuberculosis patients display polymorphisms in genes linked to the autophagy pathway, namely, the human immunity‐related GTPase M, type III interferon γ (IFN‐γ), IFN‐γ receptor, endosomal TLR8, Vitamin D3, and ATP receptor P2X7R, suggesting that some individuals might be more prone to develop tuberculosis due to a defective autophagic response.