NFKB1 and cryohydrocytosis: In addition, CHC treatment strongly reduced NF‐κB nuclear translocation in CaCO2 cells (Figure 5H), whereas there was a significant activation of NF‐κB p65 phosphorylation at Ser536 in HT‐29 and CaCO2 cells with MCT4 overexpression (Figure 5I).