Although ECG is definitely not a substitute for echocardiogram or MRI in diagnosis of CVD, we think ECG together with NT‐proBNP can somehow play an alternative role in determination of hs‐cTn 99th percentile URL.28, 36 Meanwhile, hs‐cTnT was associated with some diseases such as atrial fibrillation,45 which could be excluded by ECG not echocardiogram or MRI. This evidence concerns the gene NPPB and atrial fibrillation.