To summarize, the objective of our study was to establish 99th percentile URLs of hs‐cTnT (Roche Diagnostics) under both 2018 AACC/IFCC criteria and improved selection criteria through questionnaire survey, physical examination, and laboratory screening to further exclude hypertension, overweight and obesity, and dyslipidemia in a Chinese population, further judging whether two 99th percentile URLs of hs‐cTnT established are different. Here, MAP3K14 is linked to obesity due to melanocortin 4 receptor deficiency.