From the results we found, the expression of EMT-related markers (E-cadherin, N-cadherin and vimentin) was positively correlated with NRP1, and under the action of ionizing radiation, NRP1 promoted EMT transformation of tumor cells, thereby enhancing the metastatic ability of tumor cells which in turn enhances radiation resistance (Figure 6D). The gene discussed is CDH1; the disease is neoplasm.