Before matching, univariate analysis revealed that the PT, AST, ALBI grade, Milan criteria, AFP, tumor extent, tumor number and tumor size factors influenced the OS rates, while multivariate analysis identified PT (P=0.03), AST (P=0.034), TBIL (P=0.022) and tumor number (P=0.001) as independent risk factors. The gene discussed is AFP; the disease is neoplasm.