IL6 and neoplasm: In tumor tissue, the number of FoxP3+ Tregs was positively correlated with IL-6 expression (Figure 3B) and negatively correlated with IL-2 and TNF-α expression (Figure 3A) (R2 = 0.0720, P = 0.0161; R2 = 0.1030, P = 0.0037; and R2 = 0.0507, P = 0.0446, respectively).