In polycythemia vera, a myeloproliferative disorder characterized by a high occurrence of thrombosis, there is a correlation between the mutation of the janus kinase and phosphorylation of B-CAM/LU, which in turn initiates the interaction with endothelial laminin alpha 5 (Wautier et al., 2007; Wautier and Wautier, 2013). This evidence concerns the gene BCAM and acquired polycythemia vera.