Gentiopicroside (GPS). It has been proved that in bronchoalveolar cells isolated from fluids of lungs pulmonary fibrosis in a mouse model, GPS decreased the levels of proinflammatory cytokines, including TNF-α and IL-1β, and downregulated TGF-β1 and CTGF expression. This evidence concerns the gene TGFB1 and pulmonary fibrosis.