MRC1 and Familial prostate cancer: In addition, CSF1R and the macrophage activation marker CD206 correlated with the monocarboxylate lactate transporter MCT4 (SLC16A4) in late-stage prostate cancer (Gleason score 3+4, 4+3 and ≥8), as shown in Fig. 1a and Supplemental Fig. S1B, C.