Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculites (AAV) are autoimmune systemic diseases characterized by necrotizing inflammation of small to medium-sized vessels associated with the detection of myeloperoxidase (MPO) or proteinase-3 (PR3) -ANCAs in serum [1,2,3]. This evidence concerns the gene MPO and anti-neutrophil cytoplasmic antibody-associated vasculitis.