In the issue of antitumoral immune cells, for example, it is useful to cite Tittarelli et al. [158], who verified that Cx43, the main GJ protein of the immune system [159], accumulates at the contact zone of natural killer (NK) cells and dendritic cells (DCs) or at the interface between NK cells and target tumoral cells, facilitating DC-mediated NK cell activation and cytotoxic activity against tumor cells. Here, GJA1 is linked to neoplasm.