This work demonstrates: (1) the successful delivery of drug/gene therapy with sorted chiral SWCNTs; (2) the potential for locating each therapeutic agent separately through characteristic SWCNT fluorescence; and (3) the improved efficacy of both therapeutics when delivered with SWCNTs with substantially increased effect of SWCNT/PX866 over PX866 alone and high (over 90%) apparent knockdown of CCR5 siRNA when carried by SWCNTs, suggesting a promising potential of these formulations for combination NASH therapy. The gene discussed is CCR5; the disease is metabolic dysfunction-associated steatohepatitis.