ENO1 and breast cancer: Although the mechanisms regulating MBP-1/ENO1 ratio are not fully understood, several factors such as hypoxia [62], Endoplasmic Reticulum stress [63] and glucose concentrations [64] were described to influence MBP-1 and ENO1 transcription, strongly suggesting that posttranscriptional mechanisms might play a role in the regulation of MBP-1 expression in breast cancer cells.