Univariate logistic regression analysis of our routine clinical and biochemical measures, as well as the measured circulating cytokines and angiogenic markers, showed that the following variables significantly discriminated PDAC patients from BC participants: Male gender, GGT, total bilirubin, CA19-9, CEA, GM-CSF, IFN-γ, IL-8, IL-15, CXCL10 (IP-10), MIP-1β, bFGF, sVEGF-R1, VEGF/sVEGF-R1 ratio and sVEGF-R1/sVEGF-R2 ratio. The gene discussed is CXCL8; the disease is breast cancer.