As the first two susceptibility loci found to be associated with myopia [6, 8, 9, 12, 18, 57, 58], GJD2 [59, 60] and RASGRF1 [13, 17, 61] were significantly associated with HM in those with HM and MMD in the current study and previous studies. This evidence concerns the gene RASGRF1 and myopia.