ATP7A and infection: As expected, only infection with the MC1 TT strain induced DNA damage as assessed by a significant increase in the percentage of cells expressing early (KAP1 phosphorylation) and late (CHK2 and p53 phosphorylation) markers of DDR activation (Figures S2), therefore, the data relative to infection with the control MC1 ΔcdtB strain will not be included in the subsequent figures.