RASSF1 and neoplasm: Several studies have identified functional roles for RASSF1A‐mediated tumour suppression that can explain these clinical associations, e.g. Hippo pathway regulation (Matallanas et al, 2007; Hamilton et al, 2009), apoptosis (Vos et al, 2000; Baksh et al, 2005), differentiation (Papaspyropoulos et al, 2018), the cytoskeleton (Liu et al, 2003; Dallol et al, 2004; Vlahov et al, 2015) and DNA damage/repair (Pefani et al, 2014, 2018; Donninger et al, 2015).