To date, there is no information on any identification of markers such asIDH1/2, H3F3A G34R/V, and FGFR2 in SCA.Pilocytic astrocytomas of the spinal cord were shown to be associated withmutations in the BRAF, CDKN2,NF1, and PTEN genes, while malignant gradesIII–IV SCA variants are associated primarily with H3F3AK27M (mostly young patients and children), TP53, andPTEN [32]. This evidence concerns the gene TP53 and autosomal dominant cerebellar ataxia.