The driver for the development of primary care focussed cow’s milk allergy (CMA) guidance was the limitations of the scope of the NICE guideline, which did not include management of food allergy, nor any specific detail relating to the challenges of identifying and diagnosing milk allergy, which can present with diverse clinical symptoms, due to either an underlying IgE or a non-IgE mediated mechanism. Here, IGHE is linked to food allergy.