Wild type (WT) <i>KIT</i> and <i>PDGFRα</i> GISTs constitute a clue for a hypothetical underlying germline condition.<h4>Case presentation</h4>We present a case of a 20 years old female diagnosed of a gastric WT GIST who developed hepatic metastases during her clinical course. This evidence concerns the gene KIT and gastrointestinal stromal tumor.