Intriguingly, when 96 HCC tumors were classified into subgroups by TH or not (Figure 3A), HCC tumors with TH showed even higher expression of BOLA2 (1.748 ± 0.118 versus 2.317 ± 0.135, P<0.01; Figure 3B). This evidence concerns the gene BOLA2 and hepatocellular carcinoma.