ALDH1A1 and cancer: In accordance with the results of cancer cell analysis, this experiment revealed diminished expression of AKR1C1 (FC=1.6-2.4) and ALDH1A1 mRNAs (FC=1.7), as well as upregulation of ALDH1A3 mRNA in xenograft tumors (FC=1.7-4.0) (Figure 1C).