The mean CD59 concentrations (in ng/mL) in serum of prostate cancer patients with bone metastasis, prostate cancer without metastasis and benign prostatic hyperplasia were 57.94 (± 17.05), 28.92 (± 6.35), and 15.79 (± 5.29), respectively. The gene discussed is CD59; the disease is benign prostatic hyperplasia.